Plew is a small unincorporated community in western Lawrence County, Missouri, United States. Plew (pronounced "Ploo") is located on former U.S. Route 66, now Route 96.
The town dates back to the early 1890s, but the origin of the name is unknown (plew is a slang term for a beaver pelt, so the name may derive from the rich history of trapping and fur trading in Missouri). Occasionally it was known as "Plewtite" which may have been a family name. A couple of businesses were once located here, but the town has now dwindled to a small residential community.
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